本文聚焦三阴性乳腺癌（TNBC）治疗困境，针对ID4蛋白在基底样乳腺癌（BLBC）中的促癌机制不明问题，研究者通过CRISPR-Cas9基因编辑、小分子抑制剂AGX51干预及多组学分析，首次揭示ID4通过抑制BRCA1表达和激活ERK信号驱动肿瘤侵袭性，其靶向降解可诱导癌细胞向管 ...

Volkswagen Group has ordered dealers in the U.S. and Canada to stop selling its ID4 electric compact crossover because its doors might open while in motion, and the German carmaker doesn’t yet have a ...