A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Cancer cells rewire their metabolism to support rapid proliferation, survival under stress and metastatic spread. This reprogramming encompasses a shift from mitochondrial oxidative phosphorylation to ...

Thyroid cancer cells undergo profound metabolic reprogramming to support rapid proliferation, survival under stress and metastatic spread. A hallmark of this reprogramming is the shift from ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Leuven, 11 March 2025 – Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Poster presentation to showcase PLT012 targeting CD36 in metabolic dysfunction-associated steatohepatitis (MASH) Data demonstrate broad immune-metabolic reprogramming and reduction in key ...

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progr ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer ...

GLP-1 drugs commonly used for weight loss and diabetes decreased the risk of cancer spreading in patients with several different types of tumors including breast and lung ...

Distinct cellular interactions in the TNBC tumor microenvironment in association with PD-L1 expression and pathologic complete response based on spatial analysis. This is an ASCO Meeting Abstract from ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...