Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organize and reorganize ...

Calcineurin is a ubiquitous serine/threonine phosphatase that decodes calcium signals to regulate an array of cellular functions. Its activation requires calcium binding to calmodulin and the ...

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

UNC researchers discovered how a key step in cell signaling works by showing exactly how G proteins detach from receptors that many common medicines target. Subscribe to our newsletter for the latest ...

Scientists find that close interactions between the mechanical properties of tissues and biochemical signalling between cells ...

The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...