最值得关注的是，该突变发生在非编码 DNA 区域 —— 人类 98% 的 DNA 不编码基因，曾被视为 “垃圾 DNA”，如今证实其像软件一样调控基因激活与蛋白质合成。此次突变的是名为 Enh13 的非编码调控元件，它是转录因子的 ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Inocras and the Broad Institute analyzed 8,000+ TCGA cancer genomes to uncover new drivers and create a harmonized dataset ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked in genetic studies. Until recently, most research has investigated causes ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.