最值得关注的是，该突变发生在非编码 DNA 区域 —— 人类 98% 的 DNA 不编码基因，曾被视为 “垃圾 DNA”，如今证实其像软件一样调控基因激活与蛋白质合成。此次突变的是名为 Enh13 的非编码调控元件，它是转录因子的 ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...

Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Scientists have found new genetic causes for diabetes in babies—in a part of the genome that has historically been overlooked in genetic studies. Until recently, most research has investigated causes ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

The human genome contains about 20,000 protein-coding genes, but that only accounts for roughly two percent of the genome. For many years, it was easier for scientists to simply ignore all of that ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.