Nanoparticles introduced into the bloodstream encounter the immune complement system, a proteolytic cascade that bridges innate surveillance and adaptive responses. Complement activation can occur via ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

IIT Kanpur scientists have unlocked the mystery behind the C5aR2 immune receptor's unique function. Using advanced cryo-EM, ...

Researchers identified the immune cGAS-STING pathway as a key contributor to harmful inflammation. Using a humanized mouse model of Huntington disease, they found that blocking this pathway – either ...