当单细胞图谱遇上序列到功能模型，我们是否正在接近一个更具体的问题：非编码DNA如何在不同细胞、不同疾病状态中写出不同的表达程序？ 5月25日，《Nature Methods》的研究报道“Decoding sequence determinants ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

A new study presents “Evo” – a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo’s ability to ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning organism also requires precise instructions about when, where, and how ...

With GROVER, a new large language model trained on human DNA, researchers could now attempt to decode the complex information hidden in our genome. GROVER treats human DNA as a text, learning its ...

A new study by scientists at deCODE Genetics shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to various diseases and other ...

The scientists at deCODE Genetics, a subsidiary of Amgen, sought to deepen the understanding of cis-acting influences of sequence variants on CpG methylation. In the study, the scientists were able to ...

A new study by scientists at deCODE Genetics, a subsidiary of Amgen, shows that sequence variants drive the correlation between DNA methylation and gene expression. The same variants are linked to ...