CNS toxicity remains one of the leading causes of failure in drug development, yet it is rarely detected in preclinical studies. Among these risks, seizure liability is one of the most challenging and ...
Contrary to prior work, principal axes of structural and functional connectivity are established early in life, remaining stable and undergoing refinement throughout development.
CRISPR-based screening in drug discovery provides a robust methodology for unbiased, high-throughput interrogation of gene function. This technology enables researchers to identify and validate ...
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