Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by ...

A subtle failure during cell division can set off dramatically different outcomes, according to new research exploring whole ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Researchers at Umeå University show how tick-borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates ...

Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that ...

More than 500,000 people in the United States die each year of cancer-related causes. Now, emerging research has identified the mechanism behind one of the most common mutations that help cancer cells ...