Chromosomal microarray testing is a powerful tool for detecting genomic copy number aberrations. Combinatorial use of fluorescent dyes and oligonucleotide probes has enabled the detection of invisible ...

The causes of PS are unknown, but it has been hypothesized that the syndrome is a result of somatic mutations, which are lethal in the non-mosaic state. 8 A genome-wide scan could reveal genetic ...

Targeting ER-Golgi homeostasis as a therapeutic strategy in lung cancer. Background: In the routine diagnostic of cancers, the monitoring of the transcriptome and the chromosomal abnormalities becomes ...

Oxford Gene Technology (OGT), The Molecular Genetics Company, held an exclusive workshop exploring the power of exon-focused microarrays in enhancing genetic syndrome research at the recent European ...

BOSTON, Nov. 1, 2012 /PRNewswire/ -- Cartagenia, the world leader in providing genetic labs and clinicians software-based workflow support for variant assessment, lab reporting, and integration of ...

Agilent Technologies Inc. has announced the introduction of its SurePrint G3 Microarrays. These third-generation Agilent microarrays contain up to one million probes on a standard 1in. x 3 in. glass ...

Copy number variation (CNV) assessment is a critical component of precision medicine in almost all cancer types. For instance, copy number gain is a well described drug resistance mechanism to ...

The evolutionary history of dogs (Canis lupus familiaris), domesticated over 14,000 years ago, includes artificial selection, population bottlenecks, and inbreeding, which has resulted in over 400 ...

Numerous studies have shown that homologous recombination deficiency (HRD) is a genome-wide biomarker present in high grade ovarian and breast cancers. A cancer therapeutic class, PARP inhibitors, ...

MADISON, Wis.--(BUSINESS WIRE)-- Roche NimbleGen (SIX: RO, ROG; OTCQX: RHHBY) announced today that Seoul-based genomic services provider Macrogen, Inc. has officially joined the Roche NimbleGen ...