The development of methods for imaging large contiguous volumes with the electron microscope could allow the complete mapping of a whole mouse brain at the single-axon level. We developed a method ...

To ensure that the tissue structures of biological samples are easily recognizable under the electron microscope, they are treated with a staining agent. The standard staining agent for this is uranyl ...

The techniques used in optical microscopy are important to ensure that a sample can be viewed as clearly as possible. This will provide information about its microscopic appearance. An optical ...

Left, a tissue sample dyed by traditional methods. Centre, a computed stain created from infrared–optical hybrid imaging. Right, tissue types identified with infrared data; the pink in this image ...

Researchers performing cryo-EM experiments can acquire the training to make their own cryo-EM and negative-stain grids, and collect and process their own high-resolution data. We also offer sample ...

To ensure that the tissue structures of biological samples are easily recognisable under the electron microscope, they are treated with a staining agent. The standard staining agent for this is ...

For centuries, scientists have used microscopes to magnify and peer into a world invisible to the naked eye. The earliest instruments were simple lens-filled tubes, the best of which revealed the ...

Optical microscopy is a technique employed to closely view a sample through the magnification of a lens with visible light. This is the traditional form of microscopy, which was first invented before ...

Which compound microscope is best? Anybody who is into science has probably thought about getting a microscope. But with so many different types available, it can be overwhelming to decide on the ...

Which compound microscope is best? Anybody who is into science has probably thought about getting a microscope. But with so many different types available, it can be overwhelming to decide on the ...