Diagnosis of GERD is particularly challenging in adults who do not respond to PPI therapy and in children; careful assessment and phenotyping of patients presenting with reflux symptoms can reduce ...

Patients who are unresponsive to 4–8 weeks' treatment with PPIs twice daily might have so-called refractory GERD. The first investigation these patients should undergo is upper endoscopy to exclude a ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

If you have been suffering from prolonged acidity, heartburn, unexplained weight loss and changes in bowel pattern, chances are your doctor might want to go for a detailed investigation of your ...

Endoscopy is one of the most important tools in modern medicine, quietly transforming the way doctors diagnose and treat diseases. What once required major surgery can now often be done with a thin, ...