Inflammatory bowel disease (IBD) is a progressive, recurrent gastrointestinal disorder influenced by genetic, immunoregulatory and environmental factors and often requiring surgery for treatment.

Phase I Study of Adoptive T-Cell Therapy Using Antigen-Specific CD8+ T Cells for the Treatment of Patients With Metastatic Melanoma Two hundred fifty-one neuroblastoma specimens were analyzed using a ...

Oligonucleotide microarray (DNA chip)–based hybridization analysis is a promising new technology which potentially allows rapid and cost–effective screens for all possible mutations and sequence ...

Use of Agilent’s custom microarrays in the SOMAscan® assay will help drive biomarker discovery efforts as well as novel diagnostics and accelerated pharmaceutical development SANTA CLARA, Calif. & ...

Chromosome rearrangements are commonly associated with multiple disease states such as cancer and many developmental syndromes, including Down’s syndrome and autism spectrum disorders. The ...

A number of companies are using the lessons and technologies of traditional genomics--the microarray chief among them--to delve into the more challenging world of functional genomics and proteomics.

BETHESDA, Md. (July 22, 2004) -- Microarray technology, sometimes referred to as biochips, has been extensively used to investigate genome-wide expression patterns and has facilitated a revolution in ...

Throughout his career, Luke Dannenberg, PhD, has held multiple positions in industry and academia that have put him in close proximity to oligonucleotide technologies. Trained as a scientist, he ...

An exhaustive algorithm for detecting copy number aberrations and large structural variants in whole-genome, mate-pair sequencing data. This is an ASCO Meeting Abstract from the 2014 ASCO Annual ...

In releasing its DualChip microarray system, Eppendorf https://www.eppendorf.com of Hamburg, Germany, has blurred the lines between cDNA and oligonucleotide probes. The system makes use of Eppendorf's ...

A microarray is a two-dimensional arrangement of biological samples allowing for high-throughput analysis of genetic information. DNA microarrays are commonly used to genotype multiple regions of a ...

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...