A new single-cell atlas shows how epigenetic changes reshape brain cells during aging, revealing genomic instability, ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

We combine advanced technologies such as spatial transcriptomics, multiplexed imaging, and in situ sequencing to map cellular components in their native tissue context. Obtain high-resolution data ...

Salk researchers used spatial transcriptomics to map where different cell types reside in the mouse brain. Shown are excitatory neurons (left, blue), inhibitory neurons (middle, red), and non-neuronal ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...