A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Inflammatory bowel disease (IBD) is an umbrella term for Crohn's disease and ulcerative colitis, which both involve chronic inflammation in the digestive tract. IBD affects millions of people and ...

Spatial-biology tools are collecting more comprehensive data, and companies that want to model cells in silico are hoovering ...

Breakthrough research details how distinct tissue niches and cell communication contribute to chronic active lesions in MS. Study: Cell type mapping reveals tissue niches and interactions in ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Key opportunities in the Global Spatial Genomics and Transcriptomics Market include technological advancements in spatial ...

Spatial transcriptomics data from osteosarcoma cells. Left) A spatial map of the transcriptome segmented into individual cells using machine learning, with each dot representing a RNA transcript and ...