Tissue microarray (TMA) technology has transformed colorectal cancer research by enabling simultaneous analysis of hundreds of tissue samples under uniform experimental conditions. In this approach, ...

In 1997, Juha Kononen, a postdoctoral fellow at the National Human Genome Research Institute, was pondering the significance of the recently developed DNA microarray. He was studying genetically ...

Analysis of histological sections of disease tissues has traditionally relied on pathologist-based scoring. In an Advanced Online Publication in Nature Medicine Camp et al. describe techniques to ...

With respect to assay development, quality assurance and, ultimately, clinical adoption, the primary subject of this review, these advantages are critical. Implicit with these advantages, TMAs enable ...

The objective of the Tissue Resources Core is to collect, prepare and distribute high-quality human tissue samples (including solid tissues, blood and other biospecimens) to researchers located on the ...

Decipher score as a predictor of response to treatment intensification in the NRG Oncology-RTOG 0534 (SPPORT) phase III randomized post-prostatectomy salvage radiotherapy trial. Continuous MMAI scores ...