Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

Researchers from the Ottawa HospitalResearch Institute and the University of Ottawa in Canada, along with researchers from the Centre for Genomic Regulation at the Barcelona Institute for Science and ...

A new study reveals why some pancreatic and colorectal tumors resist targeted anti-Wnt drugs and suggests how to overcome it, offering new hope to patients with fully treatment-resistant cancers.