Sequence alignment algorithms form the foundation of comparative genomics, structural biology and evolutionary studies by identifying regions of similarity among nucleotide or protein sequences.

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Abstract: Multiple Sequence Alignment (MSA) is a fundamental NP-hard problem in Bioinformatics, central to numerous sequence analysis tasks. Despite extensive research, existing approaches still ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

Abstract: Sequence alignment is the core of many bioinformatics tasks such as read mapping, genome assembly, variant detection and so on. With the advent of the third generation sequencing, classical ...

11+ years of experience both in software development and architecture for highload B2B and B2C projects. 11+ years of experience both in software development and architecture for highload B2B and B2C ...

Current methods of assessing the similarity between proteins are based on protein sequence alignment. However, alignment is ineffective for intrinsically disordered regions (IDRs) given their rapid ...