Spatial and single-cell analyses of human donor pancreata showed that PanIN epithelial cells gradually acquire cancer-like molecular features, while their surrounding stromal and immune environment ...

Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.

A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

With global life expectancy steadily increasing, the growing gap between lifespan and healthspan has placed the aging of the ...

Transcriptomics of two prevailing models, cuprizone (CPZ) and lysophosphatidylcholine (LPC), reveal understanding of myelin loss and regeneration.

A new study may pave the way toward more personalized treatments for patients with high-risk bladder cancer, according to a study published in European Urology.

Multidimensional analyses demonstrate that repeated DeltEx DRI dosing preserves immune function, drives tumor microenvironment remodeling, and correlates with improved survival ou ...

IgA nephropathy (IgAN) is a leading cause of kidney failure driven by aberrant mucosal immunity. While the gut is the ...

Nick is a freelance writer from Chicago, IL, with a BA in Creative Writing from the University of Illinois at Urbana-Champaign. His lifelong belief in the artistic power of video games led him to ...

Do you want to generate spatial transcriptomics data using your H&E images? We introduce DeepSpot, a novel deep-learning model that predicts spatial transcriptomics from H&E images. DeepSpot employs a ...

Background Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer with highly variable malignant potential. Current understanding of their biology remains ...

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM) - Jacques E. Dumont, Belgium; ULB Institute of Neuroscience (UNI), Université Libre de Bruxelles (ULB), Belgium; ...